This agent is a smooth gel filler that your doctor uses to instantly smooth away wrinkles around your mouth and nose. Often with just one treatment, you’ll get smooth and natural looking results that last up to 9-12 months. Young, healthy looking skin contains an abundance of a naturally hydrating substance called hyaluronic acid (HA). But as you age, sunlight and other factors can reduce the amount of HA in your skin. The lack of HA causes your skin to lose structure and volume, creating unwanted facial wrinkles and folds. Using dermal filler like Juvederm® is a safe and effective way to replace the HA your skin has lost, bringing back its volume and smoothing away facial wrinkles and folds.